José V. Torres, Ph.D.

 

Education:

 1981: B.S., Biology, University of Puerto Rico at Mayagüez.

1984: M.S., Immunology, State University of New York at Buffalo.

1989: Ph.D., Microbiology and Immunology, Baylor College of Medicine, Houston, Texas.

Academic Appointments:

 7/03 - Present: Professor (Tenure), Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis.

 7/97 – 7/03: Associate Professor (Tenure), Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis.

 8/92 - 7/97: Assistant Professor, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis.

 12/91 - 8/92: Assistant Adjunct Professor, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis.

 Research Interests:

 Prophylactic and Therapeutic Cancer Vaccines

Cancer Immunology

Cancer Immunotherapy

Cancer Prevention and Education

 Selected Publications

 1.    Anderson, D. and Torres, J.V. SRV Receptor and Neutralization Mechanism by Antibodies to the Envelope Glycoprotein. Viral Immunology, 12(1):47-56.  1999

2.    Vu, HM, Myers, D, de Lorimier, R, Matthews, TJ, Moody, MA, Heinly, C, Torres, JV, Haynes, BF and Spicer, L. Nuclear Magnetic Resonance Analysis of Solution Conformations in C4-V3 Hybrid Peptides Derived From Human Immunodeficiency Virus (HIV) Type 1 gp120: Relation to Specificity of Peptide-induced Anti-HIV Neutralizing Antibodies. Journal of Virology, 73(1):746-750.  1999

3.    Muñoz, J.F., Salmen, S., Carlos, M.P., Berrueta, L.R., Cova, J.A., Donis, J.H., Hernández, M.R, and Torres, J.V.  Effect of HIV-1 on Intracellular Activation and Superoxide Production by Neutrophils.  The Journal of Infectious Diseases, 180(1):206-210.  1999

4.    Meyer, D. and Torres, J.V.  Induction of Cytotoxic and Helper T Cell Responses by Modified Variability Peptides. Viral Immunology, 12(2):117-129.  1999

5.    Meyer, D. and Torres, J.V.  Hypervariable Epitope Construct: A Synthetic Immunogen That Overcomes MHC Restriction of Antigen Presentation.  Molecular Immunology, 36(10): 631-637.  1999

6.    Carlos, MP, Yamamura, Y., Diaz-Mitoma F. and Torres, JV. Antibodies from HIV positive and AIDS Patients Bind to an HIV Envelope Variable Antigen Vaccine.  Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology, 22(4): 317-324.  1999

7.    Carlos, M.P., Anderson, D.E., Gardner, M.B. and Torres, J.V. Immunogenicity of a Vaccine Preparation Representing the Variable Regions of the HIV-1 Envelope Glycoprotein.  AIDS Research and Human Retroviruses, 16(2): 153-161.  2000

8.    Balaban, N, Singh, B, Goldkorn, T, Rasooly, A, Torres, J.V. and Uziel, O. Activation and Inhibition of the Staphylococcal AGR system (technical comment). Science, 287:391a.  2000.

9.    Leung, NJ, Aldovini, A, Young, R, Jarvis, MA, Smith JM, Meyer D, Anderson, DE, Carlos, MP, Gardner, MB and Torres, JV.  The Kinetics of Specific Immune Responses in Rhesus Monkeys Inoculated with Live Recombinant BCG Expressing SIV Gag, Pol, Env, and Nef Proteins. Virology, 268:94-103.  2000

10. Muñoz, J.F., Salmen, S., Berrueta, L.R., Carlos, M.P., and Torres, J.V.  Effect of Plasma HIV-1 RNA Levels on Neutrophil Oxidative Burst.  The Journal of Infectious Diseases, 181(3): 1214-16.  2000

11. Smith, J.M., N. Leung, and Torres J.V. Preparation and Induction of Immune Responses by a DNA AIDS Vaccine.  Viral Immunology, 13(3): 343-351.  2000

12. Miyagi,T., Chuang, LF., Doi, RH., Carlos, MP., Torres, JV. and Chuang, RY. Morphine Induces Gene Expression of CCR5 in Human CEMx174 Lymphocytes.  Journal of Biological Chemistry.  275(40): 31305-31310.  2000

13. Balaban, N., Collins, V., Cullor, J.S., Hume, E.B., Medina-Acosta, E., O'Callaghan, R.,Vieira da Motta, O., Rossitto, P.V., Serafim da Silveira L., Shirtliff, M.E., Tarkowski, A., and Torres, J.V. Prevention of Diseases Caused by Staphylococcus aureus Using the Peptide RIP. Peptides, 21 1301-1311.  2000

  1. Gov, Y., Bitler, A., Dell’Acqua, G., Torres, J.V., and Balaban, N.  RNAIII inhibiting peptide (RIP), a global inhibitor of Staphyloccocus aureus pathogenesis:structure and function. Peptides, 22(10), 1609-1620, 2001
  2. Hel Z, Nacsa J, Kelsall B, Tsai WP, Letvin N, Parks RW, Tryniszewska E, Picker L, Lewis MG, Edghill-Smith Y, Moniuszko M, Pal R, Stevceva L, Altman JD, Allen TM, Watkins D, Torres JV, Berzofsky JA, Belyakov IM, Strober W, Franchini G. Impairment of Gag-Specific CD8(+) T-Cell Function in Mucosal and Systemic Compartments of Simian Immunodeficiency Virus mac251- and Simian-Human Immunodeficiency Virus KU2-Infected Macaques. Journal of Virology. Dec;75(23):11483-95. 2001
  3. Anderson, D.E., Carlos, M.P., Nguyen, L., and Torres, J.V. Overcoming Original (Antigenic) Sin, Clinical Immunology, 101(2), 152-157, 2001

17. Smith, J.M., and Torres J.V. A Retroviral DNA Vaccine Vector. Viral Immunology, 14(4), 339-348, 2001

18. Suzuki S, Carlos MP, Chuang LF, Torres JV, Doi RH, Chuang RY. Methadone induces CCR5 and promotes AIDS virus infection. FEBS Lett. May 22; 519(1-3):173-177, 2002

19. MP Carlos, Y Yamamura, Q Vu, DE Anderson, F Diaz-Mitoma and JV Torres. Immune Evasion Strategy of HIV-1 Directed Against the Hypervariable Regions V1 through V3 of the Envelope Glycoprotein.  Proceedings of the XIV International AIDS Conference 2002.  C708F2505, 241-245, 2002

20. Rendon-Maldonado J, Espinosa-Cantellano M, Soler C, Torres JV and Martinez-Palomo A.  Trichomonas vaginalis:  In vitro attachment and internalization of HIV-1 and HIV-1 infected lymphocytes.  Journal of Eukaryotic Microbiology, 50(1): 43-48, 2003

21. Medina AL, Cova JA, Vielma RA, Pujic P, Carlos MP and Torres JV. Immunological and chemical analysis of proteins from Eisenia foetida earthworm.  Food and Agricultural Immunology, 15(3-4): 255-263, 2003

22. Torres, JV.  Vaccine Design for Emergent Viruses.  Informaceutico, 11(1): 17-20, 2004

23. Carlos MP, Yamamura Y, Vu Q, Conzen K, Anderson DE and Torres JV. Humoral immunity to immunodominant epitopes of Hepatitis C virus in individuals infected with genotypes 1a or 1b. Clinical Immunology, 111: 22-27, 2004

24. Reddy KJ, Banapour B, Anderson DE, Lee SH, Marquez JP, Carlos MP and Torres JV. Induction of immune responses against human papilloma viruses by hypervariable epitope constructs.  Immunology, 112: 321-327, 2004

25. Anderson DE, Llenado RA and Torres JV. Humoral Immunity and the Evolution of HIV-2. Viral Immunology, 17(3): 436-439, 2004

  1. Anderson, D.E., Singapuri, A, Kang, KH, Montefiori, D.C. and Torres J.V. Timing of Retroviral Infection Influences Anamnestic Immune Response in Vaccinated Primates. Viral Immunology, 18(4): 689-694, 2005

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